KEGG   Homo sapiens (human): 2011
Entry
2011              CDS       T01001                                 
Symbol
MARK2, EMK-1, EMK1, PAR-1, Par-1b, Par1b
Name
(RefSeq) microtubule affinity regulating kinase 2
  KO
K08798  MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2011 (MARK2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    2011 (MARK2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     2011 (MARK2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   2011 (MARK2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Others
     2011 (MARK2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr KA1 UBA Kinase-like ABC1 UBA_2 MELK_UBA Kdo Haspin_kinase
Other DBs
NCBI-GeneID: 2011
NCBI-ProteinID: NP_001034558
OMIM: 600526
HGNC: 3332
Ensembl: ENSG00000072518
UniProt: Q7KZI7
Structure
Position
11:63839110..63911020
AA seq 788 aa
MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG
KGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIE
TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN
LLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMK
DRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLL
LGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTS
NSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTST
NRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHP
NKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAG
QLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFRFARRNLNEPE
SKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDA
NSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIAS
KIANELKL
NT seq 2367 nt   +upstreamnt  +downstreamnt
atgtccagcgctcggacccccctacccacgctgaacgagagggacacggagcagcccacc
ttgggacaccttgactccaagcccagcagtaagtccaacatgattcggggccgcaactca
gccacctctgctgatgagcagccccacattggaaactaccggctcctcaagaccattggc
aagggtaattttgccaaggtgaagttggcccgacacatcctgactgggaaagaggtagct
gtgaagatcattgacaagactcaactgaactcctccagcctccagaaactattccgcgaa
gtaagaataatgaaggttttgaatcatcccaacatagttaaattatttgaagtgattgag
actgagaaaacgctctaccttgtcatggagtacgctagtggcggagaggtatttgattac
ctagtggctcatggcaggatgaaagaaaaagaggctcgagccaaattccgccagatagtg
tctgctgtgcagtactgtcaccagaagtttattgtccatagagacttaaaggcagaaaac
ctgctcttggatgctgatatgaacatcaagattgcagactttggcttcagcaatgaattc
acctttgggaacaagctggacaccttctgtggcagtcccccttatgctgccccagaactc
ttccagggcaaaaaatatgatggacccgaggtggatgtgtggagcctaggagttatcctc
tatacactggtcagcggatccctgccttttgatggacagaacctcaaggagctgcgggaa
cgggtactgaggggaaaataccgtattccattctacatgtccacggactgtgaaaacctg
cttaagaaatttctcattcttaatcccagcaagagaggcactttagagcaaatcatgaaa
gatcgatggatgaatgtgggtcacgaagatgatgaactaaagccttacgtggagccactc
cctgactacaaggacccccggcggacagagctgatggtgtccatgggttatacacgggaa
gagatccaggactcgctggtgggccagagatacaacgaggtgatggccacctatctgctc
ctgggctacaagagctccgagctggaaggcgacaccatcaccctgaaaccccggccttca
gctgatctgaccaatagcagcgccccatccccatcccacaaggtacagcgcagcgtgtcg
gccaatcccaagcagcggcgcttcagcgaccaggcagctggtcctgccattcccacctct
aattcttactctaagaagactcagagtaacaacgcagaaaataagcggcctgaggaggac
cgggagtcagggcggaaagccagcagcacagccaaggtgcctgccagccccctgcccggt
ctggagaggaagaagaccaccccaaccccctccacgaacagcgtcctctccaccagcaca
aatcgaagcaggaattccccacttttggagcgggccagcctcggccaggcctccatccag
aatggcaaagacagcctaaccatgccagggtcccgggcctccacggcttctgcttctgcc
gcagtctctgcggcccggccccgccagcaccagaaatccatgtcggcctccgtgcacccc
aacaaggcctctgggctgccccccacggagagtaactgtgaggtgccgcggcccagcaca
gccccccagcgtgtccctgttgcctccccatccgcccacaacatcagcagcagtggtgga
gccccagaccgaactaacttcccccggggtgtgtccagccgaagcaccttccatgctggg
cagctccgacaggtgcgggaccagcagaatttgccctacggtgtgaccccagcctctccc
tctggccacagccagggccggcggggggcctctgggagcatcttcagcaagttcacctcc
aagtttgtacgcagaaatctgtctttcaggtttgccagaaggaacctgaatgaacctgaa
agcaaagaccgagtggagacgctcagacctcacgtggtgggcagtggcggcaacgacaaa
gaaaaggaagaatttcgggaggccaagccccgctccctccgcttcacgtggagtatgaag
accacgagctccatggagcccaacgagatgatgcgggagatccgcaaggtgctggacgcg
aacagctgccagagcgagctgcatgagaagtacatgctgctgtgcatgcacggcacgccg
ggccacgaggacttcgtgcagtgggagatggaggtgtgcaaactgccgcggctctctctc
aacggggttcgatttaagcggatatcgggcacctccatggccttcaaaaacattgcctcc
aaaatagccaacgagctgaagctttaa

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Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (45)   
   RefSeq(nuc) (5)   
   GenBank (20)   
   EMBL (20)   
3D Structure (4)   
   PDB (4)   
Protein domain (10)   
   Pfam (10)   
All databases (95)   

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